Anti-IFN-gamma Mouse Monoclonal Antibody [clone: 1-D1K] (FITC)

STMC100-1459

: STEMCELL Technologies

STMC100-1459

: STEMCELL Technologies

Nom de l'antigène:
IFN-gamma
Clonalité:
Monoclonal
Clone:
1-D1K
Conjugaison:
FITC (Fluorescein Isothiocyanate)
Hôte:
Mouse
Isotype:
IgG1
Réactivité:
Non-human primates,
Human
ID de gène:
3458
Cdt:
100 Tests

Mouse monoclonal antibody against human IFN-gamma, FITC-conjugated.

Nk cells
T cells

This mouse monoclonal antibody (clone 1-D1K) reacts with human interferon-gamma (IFN-γ). IFN-γ is an ~17 kDa protein produced in response to mitogenic and antigenic stimuli by T and NK cells, and in smaller amounts by dendritic cells and macrophages. IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection (Schroder et al.). IFN-γ functions as a homodimer that is composed of interconnecting alpha-helices (Thiel et al.), which bind to the alpha subunit of the IFN-γ receptor (IFNGR) on target cells, resulting in receptor crosslinking and activation of JAK-STAT signaling (Kak et al.). IFN-γ mediates many cellular effects, including upregulation of class I and II antigen presentation pathways, antiviral and antimicrobial mechanisms, antiproliferative and apoptotic effects, immunomodulation, and leukocyte trafficking (Schroder et al.).

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-IFN-gamma Mouse Monoclonal Antibody [clone: 1-D1K] (FITC)
Antigen: IFN-gamma
Clonality: Monoclonal
Clone: 1-D1K
Conjugation: FITC
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Non-Human Primate