Anti-SHIP2 Rabbit Polyclonal Antibody

STMC60143

: STEMCELL Technologies

STMC60143

: STEMCELL Technologies

Nom de l'antigène:
SHIP2
Clonalité:
Polyclonal
Conjugaison:
Unconjugated
Hôte:
Rabbit
Réactivité:
Human,
Mouse
ID de gène:
3636 (human), 16332 (mouse)
Cdt:
100 µl

Rabbit polyclonal antibody against human, mouse SHIP2, unconjugated.

Granulocytes
Subsets
Lymphocytes
Myeloid cells

SHIP2 is a 145 kDa SHIP-related protein expressed in both hematopoietic and nonhematopoietic cells. Like SH2-containing inositol phosphatase (SHIP), SHIP2 becomes tyrosine phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP2 also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human full-length 145 kDa SHIP2 protein.

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: SHIP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse