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Anti-KIT Mouse Monoclonal Antibody [clone: YB5.B8] (PE (Phycoerythrin))
Anti-KIT Mouse Monoclonal Antibody [clone: YB5.B8] (PE (Phycoerythrin))
Catalog # PRSI76-905
Supplier:  ProSci Inc.
Anti-KIT Mouse Monoclonal Antibody [clone: YB5.B8] (PE (Phycoerythrin))
Catalog # PRSI76-905
Supplier:  ProSci Inc.

Specifications

  • Type d'anticorps:
    Primaire
  • Nom de l'antigène:
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • Symbole de l'antigène:
    KIT
  • Clonalité:
    Monoclonal
  • Clone:
    YB5.B8
  • Conjugaison:
    PE (Phycoerythrin)
  • Cytométrie en flux:
    Yes
  • Hôte:
    Mouse
  • Isotype:
    IgG1 kappa
  • Réactivité:
    Human
  • Adsorption croisée:
    No
  • Formulaire:
    liquid
  • ID de gène:
    P10721
  • Synonymes antigène:
    KIT
  • Storage buffer:
    Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
  • Température de stockage:
    The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
  • Température de transport:
    4 °C
  • Purification:
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
  • Cdt:
    25 Tests

Specifications

About this item

The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDa receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.

Type: Primary
Antigen: KIT
Clonality: Monoclonal
Clone: YB5.B8
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human