- Type d'anticorps:Primaire
- Nom de l'antigène:CD80 antigen
- Symbole de l'antigène:Cd80
- Clonalité:Monoclonal
- Clone:16-10A1
- Conjugaison:FITC (Fluorescein Isothiocyanate)
- Cytométrie en flux:Yes
- Hôte:Hamster
- Isotype:IgG
- Réactivité:Mouse
- Adsorption croisée:No
- Formulaire:liquid
- ID de gène:Q00609
- Synonymes antigène:Cd80
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Température de stockage:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Température de transport:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Cdt:0,1 mg
The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
Type: Primary
Antigen: Cd80
Clonality: Monoclonal
Clone: 16-10A1
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse