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Anti-CD28 Mouse Monoclonal Antibody [clone: CD28.2] (PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®)
Anti-CD28 Mouse Monoclonal Antibody [clone: CD28.2] (PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®)
N° de catalogue PRSI76-733
Fournisseur:  ProSci Inc.
Anti-CD28 Mouse Monoclonal Antibody [clone: CD28.2] (PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®)
N° de catalogue PRSI76-733
Fournisseur:  ProSci Inc.

Spécifications

  • Type d'anticorps:
    Primaire
  • Nom de l'antigène:
    CD28 molecule
  • Symbole de l'antigène:
    CD28
  • Clonalité:
    Monoclonal
  • Clone:
    CD28.2
  • Conjugaison:
    PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®
  • Cytométrie en flux:
    Yes
  • Hôte:
    Mouse
  • Isotype:
    IgG1 kappa
  • Adsorption croisée:
    No
  • Formulaire:
    liquid
  • ID de gène:
    P10747
  • Synonymes antigène:
    CD28
  • Storage buffer:
    Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
  • Température de stockage:
    The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
  • Température de transport:
    4 °C
  • Purification:
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
  • Cdt:
    25 Tests

Spécifications

À propos de cet article

The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.

Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: CD28.2
Conjugation: PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human