Human recombinant p27 (from E. coli)
N° de catalogue PRSI91-268
Fournisseur: ProSci Inc.
Numéro CAS:
Spécifications
- Cdt:50 µG
- Type de protéine/peptide:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:N-6 His tag
- Conditions de stockage:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Synonyme de protéine:Cyclin-Dependent Kinase Inhibitor p27|CDKN1B|KIP1|Cyclin-Dependent Kinase Inhibitor 1B|p27Kip1
- Nom de la protéine/du peptide:p27
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:24.2 kD
- Sequence:Met1-Thr198
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:For Biological Assays
Spécifications
À propos de cet article
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-6 His tag