Spécifications
- Type d'anticorps:Primaire
- Nom de l'antigène:B-cell linker
- Symbole de l'antigène:BLNK
- Clonalité:Polyclonal
- Conjugaison:HRP (Horseradish Peroxidase)
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Adsorption croisée:No
- Formulaire:liquid
- ID de gène:29760
- Synonymes antigène:Src homology 2 domain-containing leukocyte protein of 65 kDa|B-cell adapter containing a Src homology 2 domain protein|B cell adaptor containing SH2 domain|B cell linker protein|cytoplasmic adapter protein|SLP-65|B-cell activation|LY57|AGM4|B-cell adapter containing a SH2 domain protein|BLNK-S|bca|B-cell linker protein|SLP65|BASH|Src homology [SH2] domain-containing leukocyte protein of 65 kD
- Modification:phospho-Tyr84
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Température de stockage:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Température de transport:4°C
- Purification:Purified by Protein A
- Cdt:100 µl
Spécifications
À propos de cet article
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: BLNK
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat