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Anti-BLNK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Anti-BLNK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
N° de catalogue BOSSBS-9687R-HRP
Fournisseur:  Bioss
Anti-BLNK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
N° de catalogue BOSSBS-9687R-HRP
Fournisseur:  Bioss

Spécifications

  • Type d'anticorps:
    Primaire
  • Nom de l'antigène:
    B-cell linker
  • Symbole de l'antigène:
    BLNK
  • Clonalité:
    Polyclonal
  • Conjugaison:
    HRP (Horseradish Peroxidase)
  • Hôte:
    Rabbit
  • ImmunoChimie:
    Yes
  • Isotype:
    IgG
  • Réactivité:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Environmentally Preferable:
  • Adsorption croisée:
    No
  • Formulaire:
    liquid
  • ID de gène:
    29760
  • Synonymes antigène:
    Src homology 2 domain-containing leukocyte protein of 65 kDa|B-cell adapter containing a Src homology 2 domain protein|B cell adaptor containing SH2 domain|B cell linker protein|cytoplasmic adapter protein|SLP-65|B-cell activation|LY57|AGM4|B-cell adapter containing a SH2 domain protein|BLNK-S|bca|B-cell linker protein|SLP65|BASH|Src homology [SH2] domain-containing leukocyte protein of 65 kD
  • Modification:
    phospho-Tyr84
  • Storage buffer:
    Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
  • Température de stockage:
    Store at –20 °C for 12 months
  • Concentration:
    1 μg/μl
  • Température de transport:
    4°C
  • Purification:
    Purified by Protein A
  • Cdt:
    100 µl

Spécifications

À propos de cet article

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].

Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500

Type: Primary
Antigen: BLNK
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat