Specifications
- Type d'anticorps:Primaire
- Nom de l'antigène:BromoDomain Adjacent To Zinc Finger Domain, 1A
- Symbole de l'antigène:BAZ1A
- Clonalité:Polyclonal
- Conjugaison:FITC (Fluorescein Isothiocyanate)
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Adsorption croisée:No
- Formulaire:liquid
- ID de gène:11177
- Synonymes antigène:Chromatin-Remodeling Factor 180|ATP-Dependent Chromatin Remodeling Protein|ACF1|ATP-Utilizing Chromatin Assembly And Remodeling Factor 1|hACF1|WALp1|Williams Syndrome Transcription Factor-Related |WCRF180
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Température de stockage:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Température de transport:4°C
- Purification:Purified by Protein A
- Cdt:100 µl
Specifications
About this item
Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.Component of the histone-fold protein complex CHRAC complex which faciliates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: BAZ1A
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat