Spécifications
- Type d'anticorps:Primaire
- Nom de l'antigène:Epidermal growth factor receptor
- Symbole de l'antigène:EGFR
- Clonalité:Polyclonal
- Conjugaison:HRP (Horseradish Peroxidase)
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Western blot:Yes
- Environmentally Preferable:
- Adsorption croisée:No
- Formulaire:liquid
- ID de gène:1956
- Synonymes antigène:PIG61|HER1|epidermal growth f|mENA|proto-oncogene c-ErbB-1|ERBB|avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell proliferation-inducing protein 61|cell growth inhibiting protein 40|receptor tyrosine-protein kinase erbB-1|ERBB1
- Modification:phospho-Ser768
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
- Température de stockage:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Température de transport:4°C
- Purification:Purified by Protein A
- Cdt:100 µl
Spécifications
À propos de cet article
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Recommended Dilutions: Western Blot: 1:100-1000; IHC-P: 1:100-500
Type: Primary
Antigen: EGFR
Clonality: Polyclonal
Clone:
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat