Anti-FANCD2 Rabbit Polyclonal Antibody
N° de catalogue BOSSBS-2738R
Fournisseur: Bioss
Spécifications
- Type d'anticorps:Primaire
- Nom de l'antigène:Fanconi Anemia Complementation Group D2
- Symbole de l'antigène:FANCD2
- Clonalité:Polyclonal
- Conjugaison:Unconjugated
- Hôte:Rabbit
- ImmunoChimie:Yes
- Isotype:IgG
- Réactivité:Human,Rat,Mouse
- Environmentally Preferable:
- Formulaire:liquid
- ID de gène:2177
- Synonymes antigène:FAD|FA4|FANCD|FACD|FA-D2|FAD2
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Température de transport:4 °C
- Purification:Purified by Protein A.
- Taille:100 μg
- Cdt:100 µl
Spécifications
À propos de cet article
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: FANCD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat