"Stemcell Technologies"

Supplier: Stemcell Technologies

Perform total nucleic acid extraction from a variety of sample types using the ErythroClear™ magnet.

Supplier: Stemcell Technologies

Immunomagnetic isolation of untouched mouse T cells

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against mouse, toad CD8a, APC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against dextran, unconjugated

Supplier: Stemcell Technologies

DAPI (4',6-diamidino-2-phenylindole dihydrochloride) is a blue-fluorescent dye that binds to AT-rich regions of double-stranded DNA.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, APC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a antibody against human, chimpanzee, common marmoset CD45RO, APC-conjugated.

Supplier: Stemcell Technologies

Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor beta (TGF-β) superfamily. BMP-2 is a disulfide-linked homodimer, acts as a ligand for complexes of type I and II BMP receptors, and primarily activates SMAD1/5/8 signaling (Nohe et al.). BMP-2 is a potent differentiation factor and directs human pluripotent stem cells (hPSCs) towards various cell types including extra-embryonic endoderm, mesenchymal cells, and chondrocytes (Pera et al.). Although BMP-2 expression is low in healthy cartilage, its expression is upregulated at the site of cartilage damage (Blaney Davidson et al.). BMP-2 induces bone and cartilage formation in vitro and is able to induce chondrogenesis in human mesenchymal stem cells (Schmitt et al.). This product is animal component-free.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against dextran, FITC-conjugated.

Supplier: Stemcell Technologies

Stem cell factor (SCF) is an early-acting cytokine that plays a pivotal role in the regulation of embryonic and adult hematopoiesis. SCF promotes cell survival, proliferation, differentiation, adhesion, and functional activation of cells at multiple levels of the hematopoietic hierarchy. Together with other cytokines such as thrombopoietin and Flt3/Flk-2 Ligand, SCF is commonly used to promote expansion of primitive hematopoietic stem cells and multi-potent progenitor cells in culture (Martin et al.; Kent et al.). In synergy with various growth factors, including IL-2, IL-3, IL-6, IL-7, G-CSF, and erythropoietin, SCF increases proliferation and differentiation of myeloid and erythroid progenitor cells and a subset of lymphoid progenitor cells (Broudy). SCF is also a primary growth and activation factor for mast cells and eosinophils. SCF exists in two biologically active splice forms: a soluble and a transmembrane isoform. Upon binding to its receptor (c-Kit tyrosine kinase receptor; CD117), it activates PI3K, JAK/STAT, and MAPK pathways. SCF and signaling from c-Kit have also been reported to play an important role in pigmentation, fertility, vasculogenesis, motility of the gut via c-Kit positive interstitial cells of Cajal, and in the migration of neuronal stem and progenitor cells to sites of injury in the brain. This product is animal component-free.

Supplier: Stemcell Technologies

Immunodensity isolation of untouched circulating tumor cells.

Supplier: Stemcell Technologies

Rat monoclonal IgG2a antibody against human, mouse, cat CD45R (B220), Alexa Fluor® 488-conjugated.

Supplier: Stemcell Technologies

For digestion of the extracellular matrix of cartilage.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human SSEA-5, PE-conjugated.

Supplier: Stemcell Technologies

Dulbecco's Modified Eagle's Medium (DMEM) with 4500 mg/l D-glucose.

Supplier: Stemcell Technologies

Rat monoclonal IgG2b antibody against mouse Gr-1 (Ly-6G/Ly-6C), PE-conjugated.