12531 Results for: "Enzo Life Sciences"

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Garcinol ≥95% (by TLC)

Supplier: Enzo Life Sciences

HAT inhibitor

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SMI-4a ≥95%

Supplier: Enzo Life Sciences

Pim1 inhibitor

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Anti-APRIL Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

APRIL (A proliferation-inducing ligand) is a member of the TNF family. APRIL stimulates B- and T-cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death.

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Corning Life Sciences

Why Choose Corning Fetal Bovine Serum?

Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.

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Anti-POU2F1 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

The POU proteins Oct-1 and Oct-2 were identified as protein activities that selectively interact with octamer DNA sequences that regulate immunoglobulin transcription. The DNA-binding domains of Oct-1 and Oct-2 are highly homologous, and both proteins bind octamer DNA with equal affinity in vitro. Oct-1 is widely expressed whereas Oct-2 expression is restricted to the lymphoid and neuronal compartments.

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[pSer78]HSP27 (human), ELISA Kit

Supplier: Enzo Life Sciences

Most comprehensive portfolio of heat shock protein (chaperone) products commercially available.

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Anandamide ≥98% (by TLC)

Supplier: Enzo Life Sciences

Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].

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N-Arachidonyl-2-chloroethylamide ≥98% (by TLC)

Supplier: Enzo Life Sciences

Cannabinoid receptor ligand.

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Linoleamide ≥98% (by TLC), white solid

Supplier: Enzo Life Sciences

Unsaturated analog of endogenous sleep inducing lipid.

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Sp-8-Br-cGMPS ≥98% (by HPLC)

Supplier: Enzo Life Sciences

cGMP agonist.

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Noladin ether ≥98% (by TLC)

Supplier: Enzo Life Sciences

Cannabinoid receptor ligand.

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PGE2 FPIA kit

Supplier: Enzo Life Sciences

For the quantitative determination of PGE2 in culture supernatants from any species.

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Anti-IL33 Rabbit Polyclonal Antibody (Biotin)

Supplier: Enzo Life Sciences

Host: Rabbit

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URB-602 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Selectively inhibits monoacylglycerol (MAG) lipase (IC50=28µM) via a noncompetitive mechanism. Does not inhibit FAAH, DAG lipase or COX-2. URB-602 selectively raises levels of 2-arachidonoylglycerol with no change in anandamide concentrationsin cells and tissues. In the same way anandamide levels were markely elevated by the FAAH inhibitor URB597 at 1µM.

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BML-259 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Potent inhibitor of Cdk5/p25 (IC50=64 nM). Also inhibits Cdk2/cyclin E (IC50=98nM).

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AH-6809 ≥98% (by TLC)

Supplier: Enzo Life Sciences

Selective prostaglandin E₂ receptor (EP₁) antagonist. Useful at concentrations up to 10 µM, at which point it starts to block PGD₂ and TXA₂ receptors.

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LY 171883 ≥90% (by HPLC)

Supplier: Enzo Life Sciences

Leukotriene D₄ antagonist

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Human recombinant p300 (catalytic domain) (from E. coli)

Supplier: Enzo Life Sciences

Produced in E. coli. Catalytic domain (aa 1284-1673) of human p300.

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Human recombinant Akt1 (GST-tag)

Supplier: Enzo Life Sciences

Produced in insect cells. Full length active enzyme.

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Human native factor Vlla (from plasma)

Supplier: Enzo Life Sciences

Isolated from human plasma and activated.

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Bupropion hydrochloride ≥98% (by TLC)

Supplier: Enzo Life Sciences

Inhibitor of dopamine and norepinephrine transporters

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Melatonin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Endogenous agonist at melatonin MT1 and MT2 receptors. Displays antioxidant and antiapoptotic effects in numerous cell types as well as beneficial effects in various neurodegenerative diseases. It protects neuronal cells from amyloid beta-mediated oxidative damage and increases survival in an Alzheimer’s disease transgenic mouse model. Melatonin directly inhibits mitochondrial permeability transition pore (IC50 = 0.8M) and reduced the loss of neurons in a rat model of transient brain ischemia.

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Gabexate mesylate ≥98% (by HPLC)

Supplier: Enzo Life Sciences

A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.

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4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)

Supplier: Enzo Life Sciences

The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).