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12531 Results for: "Enzo Life Sciences"

Fluvastatin sodium salt ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Anticholesterol agent. HMG-CoA inhibitor.

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Lyn and Syk kinase substrate

Supplier: Enzo Life Sciences

This peptide, EDPIYEFLPAKKK, was identified through phage display as a high affinity substrate for both Lyn kinase (Km=24 µM) and Syk kinase (Km=17 µM).

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HER2 Substrate,Biotin

Supplier: Enzo Life Sciences

This peptide, Biotin-Ahx-GGMEDIYFEFMGGKKK, identified by screening a degenerate peptide library, is a substrate for several kinases, including HER-2/c-neu/erb-B-2, Tie-2, cFMS, and cKit.

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PKI (14-22) amide (myristoylated)

Supplier: Enzo Life Sciences

PKA inhibitor

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VEGFR-2 Substrate (Biotin)

Supplier: Enzo Life Sciences

This peptide, Biotin-Ahx-EEEEAYGWLDF, is derived from gastrin and can be used as a substrate for KDR/VEGFR2.

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AIP

Supplier: Enzo Life Sciences

CaM kinase inhibitor

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Vinyl-L-NIO ≥95% (by TLC)

Supplier: Enzo Life Sciences

Very selective and potent neuronal nitric oxide synthase (nNOS/NOS I) inhibitor.

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AM 281 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

CB1 receptor ligand.

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Carnosic acid ≥95% (by HPLC)

Supplier: Enzo Life Sciences

PPARgamma activator. Antioxidant.

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Caffeic acid phenylethyl ester ≥97% (by HPLC)

Supplier: Enzo Life Sciences

HIV-1 integrase inhibitor

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Pentoxifylline ≥99%

Supplier: Enzo Life Sciences

PDE inhibitor

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Ganglioside GD1a disodium salt (from bovine brain) ≥98% (by TLC)

Supplier: Enzo Life Sciences

Differentiation marker for cell growth. Protein kinase C (PKC) inhibitor. The major ganglioside of the nervous system.

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Prulifloxacin ≥98%

Supplier: Enzo Life Sciences

Fluoroquinolone with broad spectrum antibacterial activity against Gram-positive and Gram-negative bacteria.

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Cyclosporin C

Supplier: Enzo Life Sciences

Immunosuppressant

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8-Isopentenylnaringenin ≥98% (by 1H-NMR)

Supplier: Enzo Life Sciences

Prenyl flavonoid. Phytoestrogen. Selective, non-steroidal estrogen receptor α (ERα) ligand. Potent inhibitor of angiogenesis in vitro and in vivo. Chemopreventive agent against cancer induced by heterocyclic amines.

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(-)-Eburnamonine ≥99%

(-)-Eburnamonine ≥99%

Supplier: Enzo Life Sciences

Antihypoxic. Vasodilator.

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Bakuchiol ≥97% (by HPLC)

Supplier: Enzo Life Sciences

PTP1B inhibitor

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Microcystis aeruginosa [D-Asp3]microcystin-LR

Supplier: Enzo Life Sciences

Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.

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[-]-Deguelin ≥95% (by HPLC)

Supplier: Enzo Life Sciences

COX-2 inhibitor

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L-α-Phosphatidylinositol-3,4-P2 ≥98% (by NMR)

L-α-Phosphatidylinositol-3,4-P2 ≥98% (by NMR)

Supplier: Enzo Life Sciences

Activator of PKC and Akt

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Z-Phe-Ala-FMK

Z-Phe-Ala-FMK

Supplier: Enzo Life Sciences

Caspase inhibitor

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Phosphoramidon

Phosphoramidon

Supplier: Enzo Life Sciences

Neprilysin inhibitor

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Z-AAF-CMK

Z-AAF-CMK

Supplier: Enzo Life Sciences

Negative control for AAF-CMK

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Demecolcine ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Demecolcine ≥98% (by HPLC)

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(-)-p-Bromotetramisole oxalate ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Potent alkaline phosphatase inhibitor. Mimics the action of orthovanadate in the potentiation of fluorouracil antiproliferative activity. Cell permeable. 

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R59 022 ≥99%

Supplier: Enzo Life Sciences

Potentiates PKC activity

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Prostaglandin A1 ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Biosynthesis from dihomo-γ-linolenic acid. Stimulates renin release. Antitumor activity. Inhibits NFκB activation in several human cell lines. Induces the synthesis of heat shock proteins. Activates PPARs in human osteosarcoma cells at 10μM.

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Epoprosterol sodium ≥98% (by TLC)

Supplier: Enzo Life Sciences

Biosynthesis in endothelial cells. Induces vasodilation, inhibits platelet aggregation by receptor-mediated stimulation of adenylate cyclase. Cytoprotective. Fibrinolytic. Half-life under physiological conditions is 2 minutes.

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15-Deoxy-δ-12,14-prostaglandin J2 ≥97% (by TLC)

Supplier: Enzo Life Sciences

Prostaglandin D2 derived nuclear peroxisome proliferator-activated receptor γ (PPARγ) ligand. Induces apoptosis in a number of cell types including human lung cancer cells, synoviocytes and macrophages. Promotes differentiation of fibroblasts to adipocytes. Antiinflammatory activity. Inhibits angiogenesis. Prevents TNFα induced leptin increase in mice. TRPA1 agonist. Serious doubts as to the biological relevance of this prostaglandin have been raised. Endogenous levels seem to be too low to have any effect as a PPARγ ligand.

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Phorbol-12,13-dibutyrate ≥99% (by HPLC)

Phorbol-12,13-dibutyrate ≥99% (by HPLC)

Supplier: Enzo Life Sciences

Widely used PKC activator (10 to 100 ng/ml).

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