29407 Results for: "ENZO LIFE SCIENCES"

Supplier: TCI

10-Bromo-7-phenyl-7H-benzo[c]carbazole ≥98.0% (by HPLC, total nitrogen)

Supplier: US Biological

Anti-TCEAL1 Goat Polyclonal Antibody

Supplier: TCI

3-Bromo-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one ≥98.0% (by GC)

Supplier: TCI

6-Cyano-9-(diethylamino)-5H-benzo[a]phenoxazin-5-one ≥95.0% (by HPLC, total nitrogen)

Supplier: US Biological

Anti-Benzo[a]pyrene-Diol Epoxide Mouse Monoclonal Antibody [clone: 9H69]

Supplier: US Biological

Anti-LXN Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Supplier: Apollo Scientific

Methyl 6-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate 97%

Supplier: Bioworld Technology

Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, which occur later in human life. 1 * 100 µG

Supplier: Enzo Life Sciences

Pentraxin 3 (PTX3), a member of the pentraxin family, is referred to as a long pentraxin and contains a unique PTX3 domain not found in C-reactive protein (CRP) or (Serum Amyloid P component) SAP. In contrast to CRP, PTX3 is produced from the major cell types involved in atherosclerotic lesions, namely vascular endothelial cells, vascular smooth muscle cells, macrophages, and nutrophils in response to inflammatory stimuli. Moreover, CRP is produced by the liver and represents a systemic response to local inflammation, whereas PTX3 is rapidly produced directly from damaged tissues and directly reflects the inflammatory state of the vasculature. PTX3 levels have been reported to be significantly elevated in acute myocardial infarction, and accordingly, statin treatment significantly decreases PTX3 levels. Due to the fact that PTX3 is able to reflect acute coronary syndrome (ACS) condition better than CRP, it is highly possible that PTX3 is a superior biomarker to predict future cardiovascular events.

Supplier: Enzo Life Sciences

Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15kDa monomer protein, GCDFP-15. The cells within the body that produce GCDFP-15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP-15 to be a highly specific and sensitive marker for breast cancer.
GCDFP-15 is expressed by apocrine sweat glands, eccrine glands (variable), minor salivary glands, bronchial glands, metaplasmic epithelium of the breast, benign sweat gland tumors of the skin and the serous cells of the submandibular gland. Breast carcinomas (primary and metastatic lesions) with apocrine features express GCDFP-15. GCDFP-15 is positive in extramammary Paget's Disease. Other tumors tested are negative.

Supplier: Enzo Life Sciences

The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Supplier: Enzo Life Sciences

Hsp27 is one of the most common members of the highly conserved and ubiquitously expressed family of small heat shock proteins (sHsp), which also includes alphaB-crystallin. It is characterized by a conserved C-terminal alpha-crystallin domain consisting of two anti-parallel beta-sheets that promote oligomer formation required for its primary chaperone function as inhibitor of irreversible protein aggregation. Hsp27 oligomerization is modulated by post-translational phosphorylation of Hsp27 at three serine residues, Ser15, Ser78, and Ser82, by a variety of protein kinases including MAPKAPK-3, PKAc-alpha, p70 S6K, PKD I, and PKC-delta. Hsp27 has been shown to inhibit actin polymerization by binding of unphosphorylated Hsp27 monomers to actin intermediate filaments. Anti-apoptotic functions of Hsp27 have also been identified through interactions with DAXX7, activation of Akt, and inhibition of apoptosome formation. Evidence suggests altered expression of Hsp27 is implicated in the pathogenesis of breast, ovarian, and prostate cancer.

Supplier: Antibodies.com

Rabbit polyclonal antibody to eNOS for WB, IHC and ICC/IF with samples derived from Human, Mouse and Rat.

Supplier: UPCHURCH SCIENTIFIC

Stainless steel and PEEK.

Supplier: ProSci Inc.

Anti-LIFR Rabbit Polyclonal Antibody

Supplier: ProSci Inc.

Anti-LIME Goat Polyclonal Antibody

Supplier: Biorbyt

Anti-LIPE Rabbit Polyclonal Antibody

Supplier: OriGene

Anti-LIPE Rabbit Polyclonal Antibody

Supplier: OriGene

Anti-LIPE Rabbit Polyclonal Antibody

Supplier: ELTEN

Wide, durable ESD safety shoes made from robust, breathable cowhide leather, reflective materials, a padded bellows tongue and collar, plus a dual-density PU/PU sole (Saftey-Grip) (3,5 mm) with exceptional non slip and good self-cleaning properties.

Supplier: Abcam

Recombinant Porin like protein BUsg_347 (from E. coli)

Supplier: US Biological

Anti-Immunoglobulin-Like Transcript 2 Mouse Monoclonal Antibody

Supplier: Avantor Fluid Handling

Bendable a low temperatures.

Supplier: Avantor Fluid Handling

Ideal for use with high-purity or corrosive fluids.

Supplier: US Biological

Anti-HNRNPCL1 Rabbit Polyclonal Antibody

Supplier: Antibodies.com

Rabbit polyclonal antibody to eNOS for WB and ICC/IF with samples derived from Human, Mouse and Rat.

Supplier: Abnova

Rabbit polyclonal antibody raised against partial recombinant Lipe.

Supplier: Biorbyt

Anti-LIPE Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-LIPE Rabbit Polyclonal Antibody

Supplier: Biorbyt

Anti-LIPE Rabbit Polyclonal Antibody