5139 Results for: "ENZO LIFE SCIENCES"

Supplier: Enzo Life Sciences

Activates PPAR alpha and the phospholipase C (PLC) signalling pathway. Stimulates peroxisomal fatty acyl-CoA oxidase activity. These effects can be blocked by staurosporine (Prod. No. ALX-380-014). Exhibits significant cytotoxic activities against numerous tumor cell lines. Binds tubulin. Inhibits angiogenesis. Reduces HIF-1alpha protein levels. Induces apoptosis. Antifungal.

Supplier: Enzo Life Sciences

Insulin sensitising agent.

Supplier: Enzo Life Sciences

A non-tumor promoting phorbol ester, which acts as a PKC partial agonist. Protects T-lymphoblastoid cells from the killing effects of HIV-1. Upregulates latent HIV-1 provirus expression and inhibits HIV infection and viral spread at the entry/fusion step of viral life cycle. Does not induce tumor formation.

Supplier: Enzo Life Sciences

For use with GFP-expressing cell lines, as well as cells expressing blue, cyan or yellow fluorescent proteins.

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

Supplier: Enzo Life Sciences

A Real-time Mitochondrial membrane Potential Assay with Superior Sensitivity. Suitable for high-throughput applications.

Supplier: Enzo Life Sciences

The GOLGI ID® Green assay kit contains a Golgi apparatus-selective dye suitable for live cell, or aldehyde-fixed cell staining. It is more faithfully localized to the target organelle, with minimal staining of the endoplasmic reticulum. Micromolar concentrations of GOLGI ID® Green dye are sufficient for staining mammalian cells, as validated with human cervical carcinoma cell line HeLa, human T-lymphocyte cell line, Jurkat, canine kidney cell line MDCK, and human bone osteosarcoma epithelial cell line U2OS.

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Enzo Life Sciences

Gold 550 [Cyanine-3E] dUTP is a cyanine-3 derivative with enhanced spectral properties. This nucleotide analogue can replace TTP in reactions in which it serves as a substrate for E.coli DNA polymerase (holoenzyme and Klenow fragment), T4 and Taq DNA polymerases, reverse transcriptase (from AMV and M-MuLV) and terminal transferase.

Supplier: Enzo Life Sciences

The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).

Supplier: Enzo Life Sciences

Gold 525 dUTP (lyophilised)

Supplier: Enzo Life Sciences

Produced in E.coli.

Supplier: Enzo Life Sciences

Bio-11-CTP (Biotin-11-cytidine-5’-triphosphate) can replace CTP for in vitro transcription reaction catalysed by T3, T7 or SP6 RNA polymerases.

Supplier: Enzo Life Sciences

Bio-16-UTP (Biotin-16-uridine-5’-triphosphate) can replace UTP for in vitro transcription reaction catalysed by T3, T7 or SP6 RNA polymerases.

Supplier: Enzo Life Sciences

The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.

Supplier: Enzo Life Sciences

Host: Rat, Isotype: IgG2a

Supplier: Enzo Life Sciences

delta-opioid receptor agonist

Supplier: Enzo Life Sciences

Potent and selective serotonin uptake inhibitor

Supplier: Enzo Life Sciences

CaM kinase inhibitor

Supplier: Enzo Life Sciences

mGluR5 antagonist.

Supplier: Enzo Life Sciences

TLR4 activator.

Supplier: Enzo Life Sciences

Prevents neurotoxicity of glutamate on neuronal cells.

Supplier: Enzo Life Sciences

PPAR ligand.

Supplier: Enzo Life Sciences

Minor constituent of hot pepper (capsicum oleoresin).

Supplier: Enzo Life Sciences

Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.

Supplier: Enzo Life Sciences

Tamoxifen metabolite

Supplier: Enzo Life Sciences

Water soluble, potent and selective AMPA/kainate receptor antagonist.

Supplier: Enzo Life Sciences

PPAR ligand

Supplier: Enzo Life Sciences

PKC activator

Supplier: Enzo Life Sciences

BCRP inhibitor