Resin, PL-CMS, StratoSpheres™
Product Details & Documents
Chloromethylpolystyrene known as merrifield resin, PL-CMS is a copolymer support for solid phase synthesis of peptides using Boc chemistry.
Boc-amino acids are typically attached to the resin as a cesium salt, although other techniques have also been used. A slight excess of acid is neutralized with cesium carbonate and the activated acid isolated by evaporation.
Other useful techniques for cleavage include saponification or hydrolysis to create free acids, trans-esterification to create methyl esters, or aminolysis to form carboxamides. PL-CMS can be used to generate a variety of other supports by the attachment of appropriate linkers, particularly through Williamson ether synthesis.
Specifications
Specifications
- Cdt:1
- Désignation:PL-CMS resin, 1% DVB, 0,6 mmol/g, 75 - 150 μm, 1 kg
Specifications
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