Human, Mouse, Rat, Non-Human Primate Desoxyribonuclease I (DNase I)

Use Deoxyribonuclease (DNase) I Solution (1 mg/ml) for routine tissue dissociation, minimizing clumping of concentrated and/or cryopreserved cell suspensions following thawing or enzymatic tissue digestion, and to eliminate DNA contaminants.

Minimise clumping of concentrated and/or cryopreserved cell suspensions following thawing with this ready-to-use-solution
Effectively eliminate DNA contaminants from dissociation medium

The activity range of this ready-to-use solution is ≥2000 units per mg of protein. Consisting of a single glycosylated polypeptide chain with two disulfide bonds, DNase I is an endonuclease that preferentially cleaves phosphodiester linkages adjacent to pyrimidine nucleotides in both single- and double-stranded DNA, yielding polynucleotides with 5’-phosphate and 3’-hydroxyl groups (Bernardi et al.).

: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Species:
Non-human primate
Human
Rat
Mouse
Enzyme name:
DNase I Solution (1 mg/ml)
Enzyme synonyms:
DNA endonuclease; DNA nuclease; Deoxyribonucleic phosphatase; Pancreatic DNase; Thymonuclease