Recombinant Influenza A Virus Neuram (from HEK293 cells)
Catalog # PRSI96-372
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:0,1 mg
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Tag sequence:His Tag
- Biological activity:Measured by its ability to cleave a fluorogenic substrate, 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid. One unit is defined as the amount of enzyme required to cleave 1 nmole of 2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid per minute at pH 7,5 at 37 °C.
- Protein synonyms:Neuraminidase|NA
- Protein/peptide name:Influenza A Virus Neuram
- Purity:>92% as determined by SDS-PAGE
- Molecular weight:46,1 kDa
- Formulation:Lyophilised, PBS, pH 7,4
- Tested applications:Western blot
Specifications
About this item
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.