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Anti-Cd80 Hamster Monoclonal Antibody [clone: 16-10A1] (FITC (Fluorescein Isothiocyanate))
Anti-Cd80 Hamster Monoclonal Antibody [clone: 16-10A1] (FITC (Fluorescein Isothiocyanate))
Catalog # PRSI76-042
Supplier:  ProSci Inc.
New Product
Anti-Cd80 Hamster Monoclonal Antibody [clone: 16-10A1] (FITC (Fluorescein Isothiocyanate))
Catalog # PRSI76-042
Supplier:  ProSci Inc.
New Product

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    CD80 antigen
  • Antigen symbol:
    Cd80
  • Clonality:
    Monoclonal
  • Clone:
    16-10A1
  • Conjugation:
    FITC (Fluorescein Isothiocyanate)
  • Flow cytometry:
    Yes
  • Host:
    Hamster
  • Isotype:
    IgG
  • Reactivity:
    Mouse
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    Q00609
  • Antigen synonyms:
    Cd80
  • Storage buffer:
    Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
  • Storage temperature:
    The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
  • Shipping temperature:
    4 °C
  • Purification:
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
  • Pk:
    0,1 mg

Specifications

About this item

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction/co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type: Primary
Antigen: Cd80
Clonality: Monoclonal
Clone: 16-10A1
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: Mouse