Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3] (FITC (Fluorescein Isothiocyanate))
Catalog # PRSI76-022
Supplier: ProSci Inc.
New Product
Specifications
- Antibody type:Primary
- Antigen name:CD40 molecule, TNF receptor superfamily member 5
- Antigen symbol:CD40
- Clonality:Monoclonal
- Clone:5C3
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Cross adsorption:No
- Form:liquid
- Gene ID:P25942
- Antigen synonyms:CD40
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:25 Tests
Specifications
About this item
The 5C3 monoclonal antibody specifically reacts with human CD40, a 48 kDa type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: 5C3
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human