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Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3] (FITC (Fluorescein Isothiocyanate))
Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3] (FITC (Fluorescein Isothiocyanate))
Catalog # PRSI76-022
Supplier:  ProSci Inc.
New Product
Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3] (FITC (Fluorescein Isothiocyanate))
Catalog # PRSI76-022
Supplier:  ProSci Inc.
New Product

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    CD40 molecule, TNF receptor superfamily member 5
  • Antigen symbol:
    CD40
  • Clonality:
    Monoclonal
  • Clone:
    5C3
  • Conjugation:
    FITC (Fluorescein Isothiocyanate)
  • Flow cytometry:
    Yes
  • Host:
    Mouse
  • Isotype:
    IgG1 kappa
  • Reactivity:
    Human
  • Cross adsorption:
    No
  • Form:
    liquid
  • Gene ID:
    P25942
  • Antigen synonyms:
    CD40
  • Storage buffer:
    Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
  • Storage temperature:
    The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
  • Shipping temperature:
    4 °C
  • Purification:
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
  • Pk:
    25 Tests

Specifications

About this item

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48 kDa type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: 5C3
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human