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Anti-Glucocorticoid Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-Glucocorticoid Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-0252R-A750
Supplier:  Bioss
Anti-Glucocorticoid Receptor Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-0252R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    Glucocorticoid receptor
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Flow cytometry:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Epitope:
    231-320/777
  • Form:
    Liquid
  • Gene ID:
    2908
  • Antigen synonyms:
    GCRST|GRL|NR3C1|Nuclear receptor subfamily 3 group C member 1|GCCR|Glucocorticoid receptor|GCR|GR
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    85 kDa
  • Storage temperature:
    Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodelling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.

Type: Primary
Antigen: Glucocorticoid receptor
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 231-320/777
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat