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Anti-IKK alpha / beta Ser180 / 181 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-IKK alpha / beta Ser180 / 181 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3236R-A750
Supplier:  Bioss
Anti-IKK alpha / beta Ser180 / 181 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3236R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    IKK alpha / beta Ser180 / 181
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Mouse
  • Form:
    Liquid
  • Gene ID:
    1147
  • Antigen synonyms:
    NFKBIKA|Nuclear factor NFkappaB inhibitor kinase alpha|IKBKA|IKK a kinase|IKKA_HUMAN|Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells|Conserved Helix Loop Helix Ubiquitous Kinase|I Kappa B Kinase 1|Nuclear factor NF kappa B inhibitor kinase alpha|IKK alpha|Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit|IKK 1|Conserved helix loop ubiquitous kinase|IkappaB kinase|IKK1|IkB kinase alpha subunit|IKK A|IKKA|I Kappa B Kinase Alpha|Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor|CHUK1|IKKalpha|TCF16|Nuclear Factor Kappa B Inhibitor Kinase Alpha
  • Modification:
    Phosphorylation (Ser180/Ser181)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    85/87 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human IKK alpha/IKK beta around the phosphorylation site of Ser180/Ser181
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.

Type: Primary
Antigen: IKK alpha / beta Ser180 / 181
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse