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Anti-FGFR1 Tyr766 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-FGFR1 Tyr766 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3136R-A750
Supplier:  Bioss
Anti-FGFR1 Tyr766 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-3136R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    FGFR1 Tyr766
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Rat,
    Mouse
  • Western blot:
    Yes
  • Form:
    Liquid
  • Gene ID:
    2260
  • Antigen synonyms:
    Heparin binding growth factor receptor|BFGFR|N sam tyrosine kinase|Fms related tyrosine kinase 2 Pfefer syndrome|FLG protein|Fibroblast growth factor receptor 1|KAL 2|FGFR 1|CD 331|FLT 2|FGFR1 phospho Y766|p-FGFR1 phospho Y766|HBGFR|KAL2|FLT2|Fms like tyrosine kinase 2|H4|N SAM|Fms related tyrosine kinase 2|Basic fibroblast growth factor receptor 1|FLG|Hydroxyaryl protein kinase|CD331 antigen|H5|CEK|C FGR|P-FLG Tyr766|FLJ14326|FLG Tyr766|H3|CD331|FGFR1|FGFR1 Tyr766|H2|Tyrosylprotein kinase|FGF Receptor 1|bFGF R|Protein tyrosine kinase|FGFBR|MFR
  • Modification:
    Phosphorylation (Tyr766)
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molecular weight:
    88 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr766
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.

Type: Primary
Antigen: FGFR1 Tyr766
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse; Rat