Human recombinant Lysosomal Pro-X Carboxypeptidase (from cells)
PRSI91-746
:
- Pk:50 µG
- Enzyme type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
- Enzyme name:Lysosomal Pro-X Carboxypeptidase
- Purity:>95% as determined by reducing SDS-PAGE
- Molecular weight:54.5 kD
- Sequence:Leu22-His496
- Formulation:Supplied as a 0.2 µm filtered solution of 20 mM NaAc-HAc, 150 mM NaCl, 10% Glycerol,pH4.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH. PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.