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Human recombinant Fructose-1,6-Bisphosphatase 1 (from E. coli)
Human recombinant Fructose-1,6-Bisphosphatase 1 (from E. coli)
Catalog # PRSI91-122
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant Fructose-1,6-Bisphosphatase 1 (from E. coli)
Catalog # PRSI91-122
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Enzyme type:
    Recombinant
  • Source:
    E. coli
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
  • Enzyme name:
    Fructose-1,6-Bisphosphatase 1
  • Purity:
    >95% as determined by reducing SDS-PAGE
  • Molecular weight:
    37.89 kD
  • Sequence:
    Ala2-Gln338
  • Formulation:
    Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20% Glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyses the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

Fusion-Tag: C-6 His tag

This recombinant protein can be used for biological assays. For research use only.