Human recombinant CTRP5 (from E. coli)
PRSI90-149
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Environmentally Preferable:
- Tag sequence:His Tag
- Storage conditions:Working aliquots are stable for up to 3 months when stored at −20 °C.
- Protein synonyms:C1QTNF5|Complement C1q Tumor Necrosis Factor-related Protein 5
- Protein/peptide name:CTRP5
- Purity:>90% (SDS-PAGE)
- Sequence:16-243
- Formulation:Lyophilized from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).
Fusion-Tag: His Tag
This recombinant proteins is for research use only.