Human recombinant UBE2C (from E. coli)
PRSI92-139
:
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:N-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:UBE2C|UbcH10|Ubiquitin Carrier Protein C|Ubiquitin-Conjugating Enzyme E2 C|Ubiquitin-Protein Ligase C
- Protein/peptide name:UBE2C
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:23.3 kD
- Sequence:Met1-Pro179
- Formulation:Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH 7.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a 179 amino acid enzyme that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2C is highly expressed in tumour tissues and at low levels in most adult normal tissues. UBE2C is required for the destruction of mitotic cyclins and for cell cycle progression. UBE2C accepts Ubiquitin from the E1 complex and catalyses its covalent attachment to other proteins. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), which has E3 ubiquitin ligase activity, and targets for destruction substrates from the preceding mitosis (Cyclin A, Cyclin B, Securin, Geminin).
Fusion-Tag: N-6 His tag
This recombinant protein can be used for biological assays. For research use only.