Human recombinant BMP Receptor IA (from Cells)

PRSI91-930

Human recombinant BMP Receptor IA (from Cells)

PRSI91-930

Pk:
50 µG
Protein/peptide type:
Recombinant
Source:
Cells
Species:
Human
Tag sequence:
C-Fc-6 His tag
Storage conditions:
Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Protein synonyms:
BMP Type-1A Receptor|BMPR-1A|BMPR1A|SKR5|ALK-3|Activin Receptor-like Kinase 3|ALK3|Bone Morphogenetic Protein Receptor Type-1A|CD292|ACVRLK3|Serine/Threonine-Protein Kinase Receptor R5
Protein/peptide name:
BMP Receptor IA
Purity:
> 95% as determined by reducing SDS-PAGE
Molecular weight:
42.1 kD
Sequence:
Gln24-Arg152
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay

Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).

This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc-6 His tag