About this item
The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO. The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.
Type: Primary
Antigen: CD45
Clonality: Monoclonal
Clone: 2D1
Conjugation: PE (Phycoerythrin)-Cyanine5
Epitope:
Host: Mouse
Isotype: Mouse IgG1, kappa
Reactivity: Human
Specifications
- Catalog No:
- 55-9459-T100
- 55-9459-T025
- Antigen symbol:
- CD45
- CD45
- Antigen synonyms:
- Leukocyte Common Antigen, LCA, Ly-5, Hle-1
- Leukocyte Common Antigen, LCA, Ly-5, Hle-1
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- PE (Phycoerythrin)/Cy5®
- PE (Phycoerythrin)/Cy5®
- Clone:
- 2D1
- 2D1
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 5788
- 5788
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Flow cytometry:
- Yes
- Yes
- Storage temperature:
- 2-8°C protected from light
- 2-8°C protected from light
Specifications
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: Merck
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: KIMBERLY CLARK
Supplier: VWR Collection