Specifications
- Antibody type:Primary
- Antigen name:Nuclear Receptor Subfamily 3 Group C Member 1
- Antigen symbol:NR3C1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 488
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Gene ID:2908
- Antigen synonyms:glucocorticoid nuclear receptor variant 1|GRL|nuclear receptor subfamily 3 group C member 1 variant NS-1|glucocorticoid receptor|GCCR|GCR|GR|nuclear receptor subfamily 3 group C member 1 variant DL-1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Immunogen:230-280/777
- Purification:Purified by Protein A
- Pk:100 µl
Specifications
About this item
Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.
Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200
Type: Primary
Antigen: NR3C1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat