Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Type: Primary
Antigen: TAG-72 / CA72.4
Clonality: Monoclonal
Clone: B72.3 CA72/733
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Cow, Dog, Human, Rat
- Catalog No:
- BNC880734-100
- BNC880734-500
- Antigen name:
- TAG-72 / CA72.4
- TAG-72 / CA72.4
- Antigen synonyms:
- CA72.4|Tumor associated glycoprotein 72
- CA72.4|Tumor associated glycoprotein 72
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 488A
- CF® 488A
- Clone:
- Clone B72.3 CA72/733
- Clone B72.3 CA72/733
- Reactivity:
- Human, Bovine, Dog, Rat
- Human, Bovine, Dog, Rat
- Host:
- Mouse
- Mouse
- Isotype:
- IgGs
- IgGs
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
: VWR Chemicals
: VWR Collection
: VWR Collection
: VWR Chemicals
: KIMBERLY CLARK
: VWR Collection
: VWR Collection
: VWR Collection