2027 Results for: "TMC HALLCREST"
Bisindolylmaleimide I ≥98% (by TLC)
Supplier: Enzo Life Sciences
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM.
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Pravadoline ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cannabinoid receptor agonist.
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4-Hydroxybenzylidenemalononitrile ≥98% (by TLC)
Supplier: Enzo Life Sciences
The tyrphostins are well known tyrosine kinase inhibitors. However, tyrphostin 8 has been shown to inhibit calcineurin (IC50=21 µM) while displaying weak inhibition of EGFR tyrosine kinase (IC50=560 µM).
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DICA ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibitor of caspase-3 and caspase-7 binding to an allosteric site and not to the active site.
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Kifunensine ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibits α-mannosidase. Inhibits asparagine-linked oligosaccharide processing. Immunomodulator.
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(S)-Mephenytoin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cytochrome P450 substrate.
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N-Arachidonoyldopamine ≥98% (by TLC)
Supplier: Enzo Life Sciences
Activator of CB1 receptor and TRPV1
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FH535 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Inhibits the recruitment of the co-activators β-catenin and GRIP1
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Monastrol ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cell permeable non-tubulin-interacting mitosis inhibitor. Blocks mitosis (IC50=14µM) by binding to the mitotic kinesin Eg5.
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(+/-)-Anatoxin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Nicotinic acetylcholine receptor ligand.
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Calpeptin ≥98% (by TLC)
Supplier: Enzo Life Sciences
Calpain and cathepsin inhibitor
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BMOV ≥96% (by TLC)
Supplier: Enzo Life Sciences
Organic vanadium complex which acts as a potent insulin mimic.
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L-744,832 ≥98% (by TLC)
Supplier: Enzo Life Sciences
Ras farnesyltransferase inhibitor. Induces tumor regression in transgenic mice with multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Induces p21 expression and arrests cells at G1. Causes enhanced mitotic sensitivity to taxol.
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Apigenin ≥97% (by TLC)
Supplier: Enzo Life Sciences
Antioxidant and chemopreventive
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Ilimaquinone ≥98% (by TLC)
Supplier: Enzo Life Sciences
ADP-ribosylation factor inhibitor
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Anandamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Endogenous [1] ligand for the CB1 receptor (CB1: Ki=52nm; CB2: Ki=1930nm [2]) and TRPV1 (Ki=5.78µM [3,4]). Inhibits NF-κB activation through direct binding to IKKβ [5] and induces apoptosis independently of cannabinoid or vanilloid receptors [6]. Activates the MAP kinase (MAPK/ERK) signalling pathway [7].
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Palmitoylethanolamide ≥98% (by TLC)
Supplier: Enzo Life Sciences
Endogenous cannabinoid. Weak ligand of CB1 (Ki=23.8µM) and CB2 (Ki=13.9µM) receptor. Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.1µM). Immunosuppressant, anti-inflammatory, anti-nociceptive and anti-convulsant in vivo. The exact mode of action has not yet been revealed. It has been suggested that PEA: i) binds to a yet to be discovered cannabinoid receptor similar to CB2; ii) administered in vivo elicits the synthesis of endogenous agonists of CB2; iii) acts as an "entourage" compound by enhancing the activity and/or by influencing the turnover of endogenous agonists of CB2, possibly but not uniquely, by inhibiting their degradation.
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Virodhamine ≥98% (by TLC)
Supplier: Enzo Life Sciences
Cannabinoid receptor ligand.
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Latrunculin A ≥98% (by TLC)
Supplier: Enzo Life Sciences
Ultra-pure; inhibits actin polymerization
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Lovastatin ≥98% (by TLC)
Supplier: Enzo Life Sciences
HMG-CoA reductase inhibitor
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N-Arachidonylglycine ≥98% (by TLC)
Supplier: Enzo Life Sciences
FAAH inhibitor
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Supplier: GRANT INSTRUMENTS
Supplier: BOCHEM
Supplier: VWR Collection
Supplier: OMEGA BIO-TEK
Supplier: DWK Life Sciences
Supplier: Thermo Fisher Scientific
Supplier: VWR Collection
Supplier: Oxford Nanopore Technologies
Supplier: Industrial Physics
Supplier: AAT Bioquest
Supplier: Integra
Supplier: Palbam
Supplier: VWR Collection
Supplier: Integra
Supplier: VWR Collection
Supplier: FACELLITATE
Supplier: NANOENTEK
Supplier: Greiner Bio-One