2371 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD22, PE­conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD5, FITC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human CD32, FITC-conjugated.

Supplier: STEMCELL Technologies

Serum-free culture kit for in vitro expansion of mouse B cells.

Supplier: STEMCELL Technologies

Animal component-free medium for freezing ES and iPS cells as single cells.

Supplier: STEMCELL Technologies

Integrated workflow containing tools to isolate and expand CD34+ progenitor cells from peripheral blood and their subsequent reprogramming to iPS cells.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of particle-free mouse cells labelled with PE-conjugated antibodies.

Supplier: STEMCELL Technologies

Immunodensity depletion of granulocytes.

Supplier: STEMCELL Technologies

Hamster (Armenian) monoclonal IgG1 antibody against mouse CD3e, PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Apoptosis staining and detection kit - 100 tests.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, cynomolgus, cow CD117 (c-Kit), PE-conjugated.

Supplier: STEMCELL Technologies

Defined, serum-free medium for neural induction of human ES and iPS cells.

Supplier: STEMCELL Technologies

Animal component-free medium and substrate for derivation and expansion of human mesenchymal stromal cells from umbilical cord tissue.

Supplier: STEMCELL Technologies

Serum-free culture supplement for expansion and differentiation of human granulocytes.

Supplier: STEMCELL Technologies

The EasySep™ Multistand allows the separation of up to four samples at one time.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, cynomolgus, cow CD117 (c-Kit), APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD3, PerCP-Cy5.5-conjugated

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD22, APC­conjugated.

Supplier: STEMCELL Technologies

Animal origin-free, serum-free, L-glutamine-free, and phenol red-free 40X culture supplement for cloning during CHO cell line development.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a antibody against mouse CD45.1, biotin-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b, kappa isotype control antibody, PE-conjugated.

Supplier: STEMCELL Technologies

Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf and Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression (Petit et al.), the activation of metalloproteases that cleave VCAM-1 (Levesque et al.), and the release of norepinephrine from the sympathetic nervous system (Katayama et al.), leading to the release or mobilization of hematopoietic stem cells from the bone marrow into the periphery. The G-CSF receptor is expressed on a variety of hematopoietic cells, including myeloid-committed progenitor cells, neutrophils, granulocytes, and monocytes. In addition to hematopoietic cells, G-CSF is also expressed in cardiomyocytes, neuronal cells, mesothelial cells, and endothelial cells. Mouse G-CSF was first purified from cultures of the WEHI-3B myelomonocytic leukemia cell line as the inducer of the terminal differentiation of WEHI-3B and other myeloid leukemia cell lines (Nicola et al.). It was later cloned in monkey COS cells from a cDNA library prepared with mRNA derived from mouse fibrosarcoma NFSA cells that produce G-CSF constitutively (Tsuchiya et al.). Binding of G-CSF to its receptor leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2a antibody against mouse CD62L (L-selectin), PE-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, APC-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG1, kappa isotype control antibody, unconjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee CD45, Pacific Blue™-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgM antibody against mouse CD49b (integrin α2), unconjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a antibody against human CD51 (integrin αV), unconjugated.

Supplier: STEMCELL Technologies

Tumor necrosis factor-α (TNF-α) is a pro-inflammatory cytokine that activates NF-kB, MAPK, and PI3K/AKT pathways. Activated T cells and macrophages are the primary producers of TNF-α in response to inflammation and infectious conditions. Many other cell types have been shown to produce TNF-α, among them B cells, NK cells, mast cells, neutrophils, dendritic cells, microglia, endothelial cells, smooth muscle cells, cardiomyocytes, and fibroblasts. TNF-α has cytotoxic effects on cancer cells in vitro by stimulating anti-tumor immuno- suppressive responses. TNF-α stimulates expression of E- and P-selectins, thus facilitating adhesion of neutrophils, monocytes, and memory T cells to activated platelets and endothelial cells (Zelová and Hosek). Other effects of TNF-α include vasodilatation and edema formation.

Supplier: STEMCELL Technologies

Rat monoclonal IgG1, kappa isotype control antibody, biotin-conjugated.