12524 Results for: "ENZO LIFE SCIENCES"

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MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.

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Anti-HSP90 Mouse Monoclonal Antibody [clone: 2D11B9]

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DnaK possesses an autophosphorylation activity and a weak 5-nucleotidase activity, cleaving the 5 phosphate groups from both ribose and deoxyribose nucleotides. The role of DnaK in ATP-dependent protein-protein interactions has been extended to normal E. coli physiology, where, like eukaryotic Hsp70 homologs, it is thought to participate in the assembly/disassembly of protein complexes.

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Highly potent and selective ETB-receptor antagonist.

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L(-)-Glutathione (reduced form)

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Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.

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Glutamate receptor ligand

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beta-Amyloid (1-40)

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NOS inhibitor

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Competitively inhibits the generation of NO from arginine and is a useful tool for inhibition of NO mediated effects. In vitro, L-NMMA inhibits relaxation of rat aorta rings induced by acetylcholine (IC50=9.5µM). In vivo, it causes a dose dependent increase in mean arterial blood pressure in anesthetized rats (EC50=16.7mg/kg).

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NOS inhibitor

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Vesicle-associated membrane protein (VAMP), also known as synaptobrevin, is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicles. Two VAMP homologs, VAMP1 and VAMP2, are differentially expressed in the nervous system. VAMP2 is found in neurons associated with autonomic, sensory and integrative functions, and in non-neuronal Langerhans islets and glomerular cells. VAMP is a component of a 20S complex implicated in vesicle docking and fusion, the formation of which involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modulated by synaptotagmin, SNAP-25, alpha-SNAP, and NSF.

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The ROS-ID® Hypoxia/Oxidative Stress Detection Kit is a specific detection system designed for functional detection of hypoxia and oxidative stress levels in live cells (both suspension and adherent) using fluorescent microscopy or flow cytometry.

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The EFLUXX-ID® Multidrug Resistance Assay Kit allows for functional detection of all three clinically relevant ABC transporter proteins MDR1 (p-glycoprotein), MRP1/2, and BCRP. The assay uses a hydrophobic, non-fluorescent compound that readily penetrates the cell membrane, where it is hydrolyzed to a hydrophilic fluorescent dye by intracellular esterases.

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Human Recombinant HGF (from Insect cells)

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Produced in E. coli. Active Matrix Metalloproteinase-8 (MMP-8, neutrophil collagenase, collagenase-2) catalytic domain from human cDNA.

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Produced in E. coli. Human 14-3-3gamma is fused at the N-terminus to a GST-tag.

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Produced in E. coli. Human 14-3-3ζ is fused at the N-terminus to a GST-tag.

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Produced in E. coli. Full length human caspase-9 (aa 1-416).

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Produced in Sf9 cells. Active, full length protein kinase C mu (PKCµ, protein kinase D, PKD) is fused at the N-terminus to a GST-tag.

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Produced in E. coli.

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Produced in E. coli. Human pro-SUMO-1 is fused at the N-terminus to a His-tag.

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Activator of CB1 receptor and TRPV1

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Produced in E. coli. Human BAP1 is fused at the N-terminus to a His-tag.

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Produced in E. coli. Human SUMO-1 is fused to a His-tag.

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Produced in E. coli. Human SUMO-2 is fused to a His-tag.

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PARP5a inhibitor

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Inhibits the recruitment of the co-activators β-catenin and GRIP1

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For the quantitative determination of 15(S)-HETE in culture supernatants, plasma, serum, and urine from any species.

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The COX-2 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours. This is the most sensitive COX-II immunoassay kit commercially available for inflammation research.