12524 Results for: "ENZO LIFE SCIENCES"
Congo red ≥95% (by HPLC), Ultrapure
Supplier: ENZO LIFE SCIENCES
beta-Amyloid dye
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RSSR ≥97% (by HPLC), crystalline powder
Supplier: ENZO LIFE SCIENCES
Supersensitive spin label
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TMH hydrochloride
Supplier: ENZO LIFE SCIENCES
Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.
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Why Choose Corning Fetal Bovine Serum?
Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.
4-Phenylchalcone oxide (synthetic) ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.
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Olomoucine ≥98%, high purity
Supplier: ENZO LIFE SCIENCES
Olomoucine is a purine derivative which acts as a potent and selective inhibitor of CDK1 (p34cdc2)/cyclin B and related kinases. It acts by competing for the ATP binding domain of the kinase. Of 35 protein kinases tested, olomoucine inhibited p33CDK2/cyclin A, p33CDK2/cyclin E, p34cdc2/cyclin B, p33CDK5/p35 and erk1 with IC50 of 7, 7, 7, 3 and 25µM respectively. The related kinases p34CDK4/cyclin D and p40CDK6/cyclin D3 were not inhibited or were less sensitive to olomoucine, IC50 > 1000 and 250µM respectively. PKC, PKA, PKG, CaM kinase II, MLC kinase, CK2, EGFR tyrosine kinase, p56lck, p56lyn, p60c-src, v-abl and insulin receptor tyrosine kinase are not inhibited or are weakly inhibited at 1mM. It delays mouse oocyte maturation and inhibits the growth of a variety of human cell lines including Rhabdomyosarcoma cell line Rh1, Rh18, Rh28 and Rh30; MCF-7, KB-3-1 and their adriamycin-resistant counterparts (IC50=18-86µM). It inhibits DNA synthesis in interleukin-2-stimulated T lymphocytes and triggers a G1 arrest similar to interleukin-2 deprivation. Can be used to synchronize cells in G1. Triggers apoptosis in target tumor cells in vitro and in vivo and in maturing cerebellar granule neurons. N9-Isopropyl-olomoucine and the negative control Iso-olomoucine are also available.
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Geranylgeranylpyrophosphate triammonium salt 1mg/ml ≥98%
Supplier: ENZO LIFE SCIENCES
Geranylgeranyl-donor.
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Prostaglandin D₂ ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Prostanoid receptor ligand.
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TRAM 34 ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
TRAM-34 is a potent and selective inhibitor of the intermediate-conductance Ca2+-activated potassium channel (IKCa). It displays immunosuppressive activity and inhibits the proliferation of endometrial cancer cells.
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(+)-Himbacine ≥98%, powder
Supplier: ENZO LIFE SCIENCES
Muscarinic acetylcholine receptor antagonist.
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Spermine tetrahydrochloride
Supplier: ENZO LIFE SCIENCES
Spermine tetrahydrochloride
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TMTH hydrochloride ≥99%
Supplier: ENZO LIFE SCIENCES
Cyclic hydroxylamine spin probe for in vivo, intraperitoneal and intravenous injections.
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1-Acetoxy-3-carbamoyl-2,2,5,5-tetramethylpyrrolidine (ACP)
Supplier: ENZO LIFE SCIENCES
Cell permeable probe for the detection of intracellular oxidative stress.
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Irinotecan hydrochloride trihydrate ≥98% (by HPLC)
Supplier: ENZO LIFE SCIENCES
Topoisomerase I inhibitor
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Anti-Proteasome 20S Mouse Monoclonal Antibody
Supplier: Enzo Life Sciences
The proteasome is widely recognised as the central enzyme of non-lysosomal protein degradation. It is responsible for intracellular protein turnover and it is also critically involved in many regulatory processes and, in higher eukaryotes, in antigen processing. The 26S proteasome is the key enzyme of the ubiquitin/ATP-dependent pathway of protein degradation. The catalytic core of this unusually large (2000kDa, 450Å in length) complex is formed by the 20S proteasome, a barrel shaped structure shown by electron microscopy to comprise of four rings each containing seven subunits. Based on sequence similarity, all fourteen 20S proteasomal subunit sequences may be classified into two groups, α and β, each group having distinct structural and functional roles. The α-subunits comprise the outer rings and the β-subunits the inner rings of the 20S proteasome. Observations of the eukaryotic proteasome and analysis of subunit sequences indicate that each ring contains seven different subunits (α7β7β7α7) with a member of each sub-family represented in each particle. Each subunit is located in a unique position within the α- or β-rings. 120S Proteasomes degrade only unfolded proteins in an energy-independent manner, whereas 26S proteasomes degrade native and ubiquitinylated proteins in an ATP-dependent manner. The native protein substrates are recognised by subunits, some with ATP binding sites, of the outer 19S caps of the 26S proteasome. The hybridoma secreting the antibody to subunits HC2, HC3, HC8, HC9, Iota and Zeta was generated by fusion of spenocytes from Balb/c mice which had recieved repeated immunisation with dinitrophenylated proteasomes.
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Anti-NNOS Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Host: Rabbit
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Anti-PAG1 Rabbit Polyclonal Antibody
Supplier: Enzo Life Sciences
Host: Rabbit
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Human recombinant SET7/9 (from E. coli)
Supplier: Enzo Life Sciences
Produced in E. coli.
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Human recombinant NEDP1 (from E. coli)
Supplier: Enzo Life Sciences
Deconjugating Enzyme (DCE)
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SU 9516 ≥95% (by HPLC)
Supplier: Enzo Life Sciences
Cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A (IC50=22nM), CDK1/cyclin B (IC50=40nM) and CDK4/cyclin D1 (IC50=200nM). Has no effect on the activity of PKC, p38, PDGFRβ and EGFR (IC50>10µM). Displays anti-proliferative and pro-apoptotic properties in tumor cells. Inhibits proliferation of growth factor-stimulated colon carcinoma cells by binding to CDK2 and thus preventing the phosphorylation of pRb and its dissociation from E2F.
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NU 2058
Supplier: Enzo Life Sciences
Competitive inhibitor of CDK1/cyclin B (IC50=5µM) and CDK2/cyclin A (IC50=12µM). Pharmacologically distinct from the relative specific inhibitor of CDK1/2 roscovitine.
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Compound E ≥98% (by HPLC)
Supplier: Enzo Life Sciences
gamma-Secretase inhibitor
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Human recombinant proteasome 19S Rpn10/S5a subunit (GST-tag) (from E. coli), GST Tag
Supplier: Enzo Life Sciences
Produced in E. coli.
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Blocking peptide for Dishevelled-2 pAb (Prod. No. BmL-DA4270) Blocking Peptide
Supplier: Enzo Life Sciences
Sequence derived from human/mouse dishevelled-2 [Cys+600-614]. Used to generate the rabbit polyclonal antiserum to dishevelled-2 (BML-DA4270).
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Blocking peptide for Glutamic acid decarboxylase pAb (Prod. No. BmL-GC3008) Blocking Peptide
Supplier: Enzo Life Sciences
Immunization and blocking peptide for Glutamic Acid Decarboxylase (GAD) antibodies (BML-GC3008 and BML-GC3108).
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Anti-BIMS/EL/L Rat Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Rat, Isotype: IgG2a
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Anti-BIMS/EL/L Rat Monoclonal Antibody
Supplier: Enzo Life Sciences
Host: Rat, Isotype: IgG2a