Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, rheumatoid arthritis (RA)

Supplier: Charles River Laboratories Cell Solutions

CD8⁺ cytotoxic T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

Human serum, systemic lupus erythematosus (SLE)

Supplier: Charles River Laboratories Cell Solutions

CryoStor® cryopreservation freeze media products have been designed to mitigate temperature-induced molecular cell stress responses during freezing and thawing.

Supplier: Charles River Laboratories Cell Solutions

A Leukopak is an enriched leukapheresis product collected from normal peripheral blood. It is composed of a variety of blood cells including monocytes, lymphocytes, platelets, plasma, and red cells. A leukopak contains a higher concentration of cells as compared to standard venipuncture collection methods or buffy coat products.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of Diabetes Mellitus 2 (DM2), the most common form of diabetes. Human mononuclear cells are collected from human volunteer donors diagnosed with DM2 under IRB approved informed consent by whole blood or leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood CD14⁺ monocytes are isolated from peripheral blood mononuclear cells (PBMCs) by either positive or negative selection using immunomagnetic cell separation procedures. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells are isolated from IRB-consented volunteer donors diagnosed with HIV or AIDS.

Supplier: Charles River Laboratories Cell Solutions

Naive T cells are isolated by depleting CD45RO^₊ cells via immunomagnetic bead separation from a freshly collected leukopheresis product. Naive T cells are phenotypically classified as CD45⁺, CD^₊, and CD45RA^₊.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of Crohn's disease (CD). Collected from IRB-consented donors diagnosed with CD.

Supplier: Charles River Laboratories Cell Solutions

CD4⁺/CD25⁺ regulatory T cells were isolated from leukapheresis product by CD127 depletion and positive selection using CD25 immunomagnetic beads. Peripheral blood cells are collected from normal human volunteers by direct collection or by using the COBE® Spectra or Spectra Optia® Apheresis System where cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.

Supplier: Charles River Laboratories Cell Solutions

CD3⁺ T cells are isolated from mononuclear cells by positive selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

The mononuclear cell is a widely used product in research and clinical applications such as in microbiology, virology, oncology, vaccine development, transplant and regenerative biology, and toxicology.

Supplier: Charles River Laboratories Cell Solutions

Neutrophils are derived from a dextran red cell sedimented population of cells. Following red cell sedimentation, granulocytes are separated using a density gradient and red cell lysis. Cells are then purified through the use of indirect selection.

Supplier: Charles River Laboratories Cell Solutions

CD56⁺ NK cells are isolated from mononuclear cells either by positive selection using an antibody that targets the CD56 antigen, or by negative selection using immunomagnetic cell separation procedures.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells used for researching the causes, diagnosis, supportive care and treatment of chronic myeloid leukemia (CML). Human mononuclear cells are collected from human volunteer donors diagnosed with CML under IRB approved informed consent.

Supplier: Charles River Laboratories Cell Solutions

Serum used for researching the causes, diagnosis, supportive care and treatment of acute myeloid leukemia (AML). Serum is collected from IRB-consented volunteer donors diagnosed with acute myeloid leukemia (AML).

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of herpes simplex virus 2 (HSV 2). Collected from IRB-consented donors diagnosed with HSV 2.

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of human immunodeficiency virus (HIV). Collected from IRB-consented donors diagnosed with HIV.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of type 2 diabetes mellitus (DM 2). Collected from IRB-consented donors diagnosed with type 2 diabetes mellitus.

Supplier: Charles River Laboratories Cell Solutions

Human mononuclear cells, chronic lymphocytic leukemia (CLL)

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of multiple sclerosis (MS). Collected from IRB-consented donors diagnosed with MS.

Supplier: Charles River Laboratories Cell Solutions

Human serum used for researching the causes, diagnosis, supportive care and treatment of hepatitis C Virus (HCV). Collected from IRB-consented donors diagnosed with HCV.

Supplier: Charles River Laboratories Cell Solutions

Plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Patient samples can be used by researchers to investigate biomarker and diagnostic development, pre-clinical research validation, and drug toxicity and efficacy. Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Collected from IRB-consented donors diagnosed with GC.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood M1 macrophages are derived from purified monocytes. CD14⁺ monocytes were isolated from peripheral blood mononuclear cells (PBMCs) using positive immunomagnetic cell separation procedures and were cultured in the presence of GM-CSF for 10 days. The M1 phenotyping was confirmed by morphology and the expression of specific biomarkers.

Supplier: Charles River Laboratories Cell Solutions

Human plasma, systemic lupus erythematosus (SLE)

Supplier: Charles River Laboratories Cell Solutions

AAV1/2 Vector with CMV promoter, Null/Empty, WPRE, bovine growth hormone (BGH), and polyadenylation sequence.

Supplier: Charles River Laboratories Cell Solutions

Mononuclear cells are critical components of the immune system which are involved in both humoral and cell-mediated immunity. The mononuclear cell is a widely used product in research and clinical applications such as in microbiology, virology, oncology, vaccine development, transplant and regenerative biology, and toxicology.

Supplier: Charles River Laboratories Cell Solutions

Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of psoriasis (PSO). Collected from IRB-consented donors diagnosed with PSO.

Supplier: Charles River Laboratories Cell Solutions

Psoriasis (PSO) is isolated from mononuclear cells collected from IRB-consented donors diagnosed with psoriasis (PSO).