mCherry mRNA encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.

• Capped with CleanCap® M6 cap analog, modified with N1-methylpseudouridines to enhance protein expression

• Cap 1 structure with >95% capping efficiency for superior in vivo activity compared to Cap-0 mRNAs
• Manufactured with CleanCap M6–specific IVT that lowers dsRNA and improves performance
• Ready to use in downstream mRNA applications and formulations

Grade: RUO

CleanCap Reagent M6, otherwise known as CleanCap m6AG 3′ OMe, produces a base-modified Cap-1 mRNA, which shows superior in vivo activity compared to Cap-0 mRNA produced by legacy capping methods such as mCap or anti-reverse cap analog (ARCA). CleanCap M6 may further increase protein expression relative to previous generations of cap analogs, such as CleanCap AG or CleanCap AG (3′ OMe), or mRNAs produced by enzymatic capping strategies.