Iodoacetamide 98% stabilised
Toxic
IrritantAbout this item
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation.
2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation
- CAS Number:144-48-9
- Formula:ICH₂CONH₂
- MDL Number:MFCD00008028
- Molecular Weight:184.96 g/mol
- Boiling Pt:266 °C (1013 hPa)
- Melting Pt:92…95 °C (dried)
- Storage Temperature:Refrigerator
- EINECS:205-630-1
- UN:2811
- ADR:6.1,III
- :Moistened with water ∼5-8%
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Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation.
2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation
- CAS Number:144-48-9
- Formula:ICH₂CONH₂
- MDL Number:MFCD00008028
- Molecular Weight:184.96 g/mol
- Boiling Pt:266 °C (1013 hPa)
- Melting Pt:92…95 °C (dried)
- Storage Temperature:Refrigerator
- EINECS:205-630-1
- UN:2811
- ADR:6.1,III
- :Moistened with water ∼5-8%
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