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Human Recombinant CCL19 (MIP-3 beta)
Human Recombinant CCL19 (MIP-3 beta)
Catalog # STMC100-0935
CAS Number:  
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Human Recombinant CCL19 (MIP-3 beta)
Catalog # STMC100-0935
CAS Number:  

Specifications

  • Pk:
    100 µG
  • Protein/peptide type:
    Recombinant
  • Species:
    Human
  • Protein synonyms:
    beta-chemokine exodus-3|CC chemokine ligand 19|ELC|Exodus-3|MIP-3β|SCYA19
  • Protein/peptide name:
    CCL19 (MIP-3 beta)
  • Purity:
    ≥95%

Specifications

About this item

Chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein-3 beta (MIP-3β), is a member of the CC chemokine family, which plays key roles in inflammatory responses, T cell activation, homeostasis, and development (Yan et al.). CCL19 is expressed in lymph nodes, thymus, and activated bone marrow stromal cells; it binds to C-C motif chemokine receptor 7 (CCR7) to induce migration of macrophages, T cells, and B cells (Gibejova et al.). Clinically, the expression of CCL19 is correlated to autoimmune diseases such as rheumatoid arthritis and cancer (Pickens et al.; Zhang et al.).

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').