Suppressor genes, such as p53, are essential for cell functions. Mutations in the p53 gene can be correlated to predisposition for certain cancers. Mutations of genes can either be inherited or accumulated due to environmental insults. This experiment deals with a family pedigree determination of several generations relating to cancer formation due to p53 gene mutation.

• For six lab groups
• Complete in 60 minutes

Also required: Electrophoresis tank, power supply, automatic micropipette with tips, 65 °C water bath, and UV transilluminator.