An Sandwich ELISA kit to quantify human TNFSF10 in human serum, plasma, culture supernatants.

• Easy, convenient and time-saving method to measure the level of TNFSF10 in human serum, plasma, tissue homogenates, culture supernatants and other biological fluids
• Detection Range: 15,6 to 1000 pg/ml
• Sensitivity: <9,375 pg/ml

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. BioVision’s TNFSF10 ELISA kit is a sandwich ELISA assay for the quantitative measurement of human TNFSF10 in serum, plasma and cell culture supernatants. The density of colour is proportional to the amount of human TNFSF10 captured from the samples.

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