L-JNKi1
Jnk inhibitor
This L-stereoisomer is a cell permeable JNK (c-Jun N-terminal kinase) inhibitor. For increased cell permeability the peptide was covalently linked to the 10 aa recognized by the TAT transporter. Neuroprotective agent for stroke. Inhibits the interaction between JNK (JNK-1, -2 and –3) and its substrate with the same IC50 (in vitro IC50 ~ 1 µM), but is degraded more readily than the D-stereoisomer, thus requiring higher treatment concentrations in vitro and in vivo.
- Pk:1 mg
- Cat. No.:ENZOBMLEI3540001
- Protein/peptide name:L-JNKi1
- Formulation:Lyophilised
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