Human recombinant MMP2 (catalytic domain)

ENZOBMLSE2370010

ENZOBMLSE2370010

Pk:
10 µG
Protein/peptide type:
Recombinant
Species:
Human
Seq:
02
Protein/peptide name:
MMP2 (catalytic domain)
Formulation:
In TRIS-HCl, pH 7,5, containing 300 mM NaCl, 5 mM CaCl2, 20 µM ZnCl2 , 0,5% Brij-35 and 20% Glycerol.

Produced in yeast. Active recombinant matrix metalloproteinase-2 (MMP-2, gelatinase A, 72kDa type IV collagenase) cloned from human cDNA.

The enzyme consists of residues Tyr110-Asp452 (NM_004530), which comprises the catalytic/fibronectin domain of human MMP-2, with a C-terminal purification tag. This represents a naturally occurring active form of MMP-2 which lacks the C-terminal hemopexin domain.

MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected.