COMET SCGE Assay measures DNA damage by fluorescently detecting the integrity of DNA liberated from cells embedded in low melting point agarose. Upon electrophoresis, fragmented DNA produces a characteristic "comet" shaped tail as small DNA fragments migrate in the gel more rapidly than in-tact genomic DNA.

• Comet Slides allow direct application of sample without pretreatment
• Higher throughput sample analysis
• Hydrophobic barrier allows sample treatment with DNA repair enzymes

For the measurement of DNA Damage, DNA Repair, and Apoptosis in cells and tissue from any species via electrophoresis.

The COMET SCGE Assay is a fast and simple electrophoresis method to detect and quantitate DNA fragmentation in cells associated with DNA damage and apoptosis. A unique nucleic acid stain provides improved sensitivity for DNA visualization compared to ethidium bromide.