About this item
The tetrapeptide KDEL, located at the carboxy-terminal sequences of luminal proteins, is a retrieval motif essential for the precise sorting of these proteins along the secretory pathway. KDEL proteins perform essential functions in the endoplasmic reticulum (ER) related to protein folding as well as assembly. The localization of chaperones and other soluble proteins to the ER is achieved by their continuous retrieval from post-ER compartments by the KDEL receptor (Erd2p), which is a membrane protein localized in the Golgi apparatus.
Recognizes proteins containing the KDEL sequence in mammals, birds, insects, plants, and yeast. Detects three bands of ~94kDa, ~78 kDa and ~55kDa by Western blot.
Type: Primary
Antigen: KDEL
Clonality: Monoclonal
Clone:
Conjugation: DyLight® 488
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Recognizes Proteins Containing The Kdel Sequence In Mammals
Specifications
- Catalog No:
- ENZOADISPA827488F
- ENZOADISPA827488D
- Antigen symbol:
- KDEL
- KDEL
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- DyLight® 488
- DyLight® 488
- Reactivity:
- Mammals
- Mammals
- Host:
- Mouse
- Mouse
- Isotype:
- IgG2a
- IgG2a
- Flow cytometry:
- Yes
- Yes
- Form:
- Liquid, in PBS containing 0,09% sodium azide
- Liquid, in PBS containing 0,09% sodium azide
- Purification:
- Protein G affinity purified
- Protein G affinity purified