Mouse recombinant IL-10 non-lytic (from CHO cells)
PRSI90-500
:
- Pk:10 µG
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Mouse
- Tag sequence:Fc Tag
- Storage conditions:Stable for at least 1 year after receipt when stored at −20 °C. Working aliquots are stable for up to 3 months when stored at −20 °C.
- Biological activity:6,000 units/ug as determined by ELISA. Bioactivity demonstrated in cytokine synthesis inhibition assay, measuring inhibition of IL-6 production by PU5-1 cells.
- Protein synonyms:Interleukin-10|Cytokine Sythesis Inhibitory Factor|CSIF
- Protein/peptide name:IL-10 non-lytic
- Purity:>98% (SDS-PAGE)
- Sequence:19-178
- Formulation:Lyophilized from 0.2um-filtered solution in PBS.
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Fusion-Tag: Fc Tag
This recombinant proteins is for research use only.