Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Species:Human
- Tag sequence:C-Fc tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:CD337|1C7|Natural Cytotoxicity Triggering Receptor 3|LY117|NCR3|Natural Killer Cell p30-Related Protein|NK-p30|Activating Natural Killer Receptor p30|NKp30
- Protein/peptide name:NCR3
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:40.2 kD
- Sequence:Leu19-Thr138
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB，150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumour cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signalling specifically induces lytic activity against several tumour cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.
Fusion-Tag: C-Fc tag
This recombinant protein can be used for biological assays. For research use only.