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Human recombinant CD300A (from cells)
Human recombinant CD300A (from cells)
  PRSI91-914
 :  
Human recombinant CD300A (from cells)
  PRSI91-914
 :  

 

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Environmentally Preferable:
  • Tag sequence:
    C-Fc-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    CD300 antigen-like family member A|NK inhibitory receptor|LMIR1|Immunoglobulin superfamily member 12|CMRF35-like molecule 8|IRC1/IRC2|CMRF35-H|CMRF-35-H9|Inhibitory receptor protein 60
  • Protein/peptide name:
    CD300A
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    45.4 kD
  • Sequence:
    Leu18-Gln178
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NACl,5% Trehalose,pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    used for biological assays

 

 

CD300A is a single-pass type I membrane protein which belongs to the CD300 family. It contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD300 family of myeloid immunoglobulin receptors includes activating (CD300b, CD300e) and inhibitory members (CD300a, CD300f), as well as molecules presenting a negative charge within their transmembrane domain (CD300c, CD300d). It is expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is an inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. CD300c is a functional immune receptor able to deliver activating signals upon ligation in RBL-2H3 mast cells.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-Fc-6 His tag