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Human recombinant SHMT1 (from cells)

Human recombinant SHMT1 (from cells)

50 µG
Catalog # PRSI91-687
Supplier:   ProSci Inc.
Human recombinant SHMT1 (from cells)
Catalog # PRSI91-687
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant SHMT1 (from cells)

50 µG

CAS Number:  
Price
730,00 €
Log in for availability
1 * 50 µG
Product Details & Documents

Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetramer. SHMT1 catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon unit for the synthesis of methionine, thymidylate, and purines in the cytoplasm. A reduction in SHMT1 levels would result in less glycine that could affect the nervous system by acting as an agonist to the NMDA receptor and this could be a mechanism behind Smith-Magenis syndrome.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag

Documents

Specifications

Specifications

  • Pk:
    50 µG
  • Protein/peptide name:
    SHMT1
  • Protein synonyms:
    Serine Hydroxymethyltransferase Cytosolic|Serine Methylase|SHMT1|SHMT|Glycine Hydroxymethyltransferase
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Sequence:
    Met3-Phe483
  • Source:
    Cells
  • Molecular weight:
    53.9 kD
  • Cat. No.:
    PRSI91-687
  • Protein/peptide type:
    Recombinant
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tag sequence:
    C-6 His tag
  • Tested applications:
    Bioassay
  • Species:
    Human

Specifications