- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Environmentally Preferable:
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:FIL1Z|Interleukin-23|IL-1H4|IL1H4|IL-1X|Interleukin-1 Family Member 7|IL-1F7|Interleukin-1-Related Protein|Interleukin-37|IL1RP1|IL-1 Zeta|Interleukin-1 Zeta|IL37|IL-1H|Interleukin-1 Homolog 4|IL-1RP1|FIL1 Zeta|IL-37|IL1F7
- Protein/peptide name:IL37
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:18.7 kD
- Sequence:Lys53-Asp218
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 2mM DTT, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Human Interleukin family 1 Member 7 (IL1F7) is a member of the Interleukin 1 cytokine family. Five alternatively spliced transcript variants encoding distinct isoforms have been reported with distinct expression profiles. The longest IL1F7 transcript, referred to as IL1F7b or IL1F7 isoform 1, encodes a 218 amino acid residues proprotein containing a 45 amino acid propeptide, which is cleaved to generate mature protein. IL1F7b binds to IL18 R alpha with low affinity but does not exert any IL18 agonistic or antagonistic effects. IL1F7b also binds interleukin 18 binding protein (IL-18BP), an inhibitory binding protein of interleukin 18 (IL-18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL-18.
- This recombinant protein can be used for biological assays. For research use only.